Preheat the oven to 350 degrees.

Cook the pasta to your liking and drain well.

Cook the ground turkey, onion, and garlic in olive oil in a skillet over medium-high heat until the meat is completely browned. Drain if needed.

Reduce the heat in the skillet to low, stir in the tomato sauce and Italian seasoning.

In a large mixing bowl, combine the meat sauce, pasta, 1 cup of cheese, and 16 slices of pepperoni. Stir to combine well.

Press the mixture into a 9x13 baking dish and top with the remaining cheese and pepperoni.

Cover in foil and bake for 20 minutes.

Uncover, and bake for an additional 10 minutes before serving.